Autoimmune Disease Detection-In Vitro Diagnostic Raw Materials-CRO Service

Autoimmune diseases occur when the immune system mistakenly attacks the body’s own cells, tissues, or organs, treating them as foreign invaders. This abnormal immune response leads to the production of autoantibodies, which target the body’s own cells, tissues, or organs, resulting in tissue damage, inflammation, and in some cases, organ dysfunction. An increasing number of studies have found that autoimmunity is associated with a variety of diseases, such as thyroid disorders, type 1 diabetes, and vasculitis.

Autoantibodies can serve as biomarkers for both the diagnosis and prognosis of autoimmune diseases. In many cases, they can be detected before clinical symptoms emerge, offering critical opportunities for selection of more effective treatment strategies. The target antigens corresponding to these autoantibodies can be utilized in various diagnostic methods (such as ELISA) to achieve highly sensitive disease detection.

Figure 1. Representative organ-specific and systemic autoimmune diseases(Image source: Wang L et al., J Intern Med., 2015)

Genevoyager High-Performance Diagnostic Raw Materials

Genevoyager has developed a range of high-quality IVD antigen materials for autoimmune disease diagnostics, widely used by leading companies in the development and production of IVD reagents. Custom production services are also available to address specific client requirements.

Supported by four well-established protein expression platforms - E. coli, yeast, mammalian cells, and baculovirus insect cell systems - and enhanced by our proprietary One-Bac 4.0 system, Genevoyager delivers diagnostic raw materials with excellent scalability, quality and batch-to-batch consistency. Combined with advanced process development capabilities and cGMP-compliant manufacturing facilities, our integrated platform ensures cost-efficiency and reliability, empowering our partners to develop impactful diagnostic solutions that meet unmet medical needs.

Why Choose Us

1. Versatile protein expression platforms

Multiple expression systems — includingE. coli, yeast, HEK293, and baculovirus insect cells (One-Bac 4.0)— enable customproteindevelopment tailored to client needs

2. Proprietary One-Bac 4.0 platform

Our advanced One-Bac 4.0 platformensures exceptional protein stability and consistency, making itideally suited for the development of high-performance IVD reagents

Product Applications

Diagnostic Antigen Portfolio

Service Process and Timeline

List of Selected Products

Cat. No.	Antigen Protein	Expression Host	Specification	Recommended Use	Applicable Disease
PEAD-0001B	GAD65	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Type 1 Diabetes (T1DM)
PEAD-0004B	ZNT8	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Type 1 Diabetes (T1DM)
PEAD-0005B	TPO	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Autoimmune Thyroid Disease (AITD)
PEAD-0007B	TSHR	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Autoimmune Thyroid Disease (AITD)
PEAD-0008B	MPO	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	ANCA-Associated Vasculitis (AAV)
PEAD-0009B	PR3	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0010B	BPI	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0011B	NC-1 alpha3	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0012B	PLA2R	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Membranous Nephropathy (MN)
PEAD-0013B	C1q	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0014B	THSD7A	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0015B	filaggrin	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Rheumatoid Arthritis (RA)
PEAD-0016B	MCV	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0017B	MMP-3	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0018B	hnRNP-A2	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0019B	CYPIID6	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Autoimmune Liver Disease (AILD)
PEAD-0020B	SepSecS	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0021B	Ro52	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0022B	sp100	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0023B	gp210	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0025B	CENP-B	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0057B	FTCD	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0026B	NMDARs	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Autoimmune Encephalitis (AE)
PEAD-0032B	Dsg1	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Bullous Pemphigoid (BP)
PEAD-0034B	Hydrogen potassium ATPase	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Pernicious Anemia (PA)
PEAD-0035B	IF	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Pernicious Anemia (PA)
PEAD-0042B	PS/PT	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Antiphospholipid Syndrome (APS)
PEAD-0043B	β2GPI-D1	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Antiphospholipid Syndrome (APS)
PEAD-0044B	MUC1	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Interstitial Lung Disease (ILD)
PEAD-0045B	Mi-2	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating	Polymyositis (PM)
PEAD-0046B	Ku（P70/P80）	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0048B	PM-scl75	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0049B	Jo-1	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0050B	PL-7	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0051B	PL-12	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0052B	SRP54	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating
PEAD-0053B	EJ	Baculovirus-Insect Cells	100ug,1mg,10mg	Standard reference materials/antigen coating

CRO Service

Autoimmune Disease Detection

Genevoyager High-Performance Diagnostic Raw Materials

Why Choose Us

Product Applications

Diagnostic Antigen Portfolio

Service Process and Timeline

List of Selected Products

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